Genetic Canine

The mutations of genes cause hereditary diseases. The Investigation of the hereditary diseases in the dogs, could help to determine that animals can take a characteristic that produces disease like by ej. displasia of the hip and atópica dermatitis.
Recently, the mutation of the gene responsible for the disease of Willebrand (a pathology that affects the coagulation of the blood, like hemofilia), has been identified in the Caniche and Manchester Terrier. The mutations of this gene that causes this disease, have been identified in the Doberman Scottish Pinschers and Terriers.

At the moment, there are tests available to determine if the dogs of these races take this mutation.
Another investigation is trying to determine genes responsible for progressive the retinal degeneration in Farmers Retrievers and Caniches; the canine epilepsy; the hipotiroidismo; the cataracts; the disease of Addison (the hipoadrenocorticismo); the hereditary nefritis in the Cocker Spaniels; and displasia of the elbow in Retrievers Farmers.

The possible thing for ?drawing up? whole the canine genome is haciéndo, as well as similar efforts were made to draw up the human genome. These maps will help to determine that genes are responsible for each one for the hereditary pathologies.
Therapeutic Genetics
Investigators of the University of Stanford and the University of Pennsylvania have treated a successfully inherited disease in dogs having used the genetic therapy. Its study involved to dogs with hemofilia with an inherited defect specific.

The correct gene was combined to a benign disease that produces the virus and it was introduced in the affected dogs. The defect of the gene was corrected partially in these dogs during 8 to 17 months depending on the used technique.
These types of treatments can avoid the death or prolong the life of the dogs with hemofilia.

Commentaries:
The possibility of identifying the genetic abnormalitys in the domestic animals would be preventive of many diseases. The genetic therapy would make the lives of domestic animals and their owners happier and more healthful.

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